Mannheim, renowned as a "UNESCO City of Music", is located in the state of Baden-Württemberg in southwestern Germany. The city boasts exceptional transportation links, as it is situated at the confluence of the Rhine and Neckar rivers. Its integrated airway, highway, and waterway networks provide rapid access to each corner of Europe and the world.

Mannheim is the cultural and economic center of the Rhine-Neckar Metropolitan Region and a historic yet vibrant industrial city. It is home to many renowned international and domestic companies, including ABB, BASF, Daimler, Roche Group, John Deere, Siemens, ThyssenKrupp, and Pepperl+Fuchs. Mannheim's industrial sector is diverse, encompassing engineering, electrical, automotive, chemical, pharmaceutical, logistics, IT technology, agricultural machinery, and specialized trades, making it a highly appealing economic hub in Germany.

Zhenjiang and Mannheim officially established their sister-city relationship on March 1, 2004. The "Chinese Garden" project, a collaboration between the two cities, is a symbol of their friendship. Hailed as "the largest Chinese garden in Europe", it also serves as a significant base for Sino-German cultural exchange.